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Biochemistry & Molecular Biology
The Biochemistry and Molecular Biology (BMB) Program integrates researchers from across Mayo Clinic’s diverse scientific strengths and provides an exceptional graduate-level educational experience. Students will learn to conduct molecular research in basic science and model organisms with the vast majority of projects directly related to human disease.
The BMB Program provides graduate training through three subtracks:
Biochemistry and Structural Biology
Cell Biology and Genetics
Cancer Biology
Current areas of BMB research include:
Endocytosis, vesicular and lipid trafficking and protein sorting
Genetic and epigenetic studies in cancer and monogenic disorders
Protein folding and diseases of abnormal folding
Biochemical, cellular and genetic analysis of heart disease
Role of centrosomes and cilia in disease
Molecular analysis of fibrosis
DNA structure and transcriptional regulation
Transcription factors and signaling cascades in cancer
Role of estrogens in osteoporosis and cancer
Epithelial biology in disease studies
Iron and calcium homeostasis
These studies employ human disease specimens and an array of model systems including mice, zebrafish, drosophila and yeast.
Aiding these studies are imaging resources for visualization at the whole organ, cellular, molecular and atomic levels, as well as state-of-the-art genomics and proteomic facilities.
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